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DNA Replication


This quiz is based on the process of DNA replication in both Prokaryotes and Eukaryotes.

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Multiple choice

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1.

In DNA, mutations at G-C sequences occur quite frequently since 5-methyl cytosine easily deaminates to form :

  Thymine

  Adenine

  Guanine

  Cytosine

  Half-n-half Clue
 

2.

The enzyme that creates a short RNA oligonucleotide at initiation sites where replication is to be carried out is called :

  Primase

  DNA Ligase

  DNA Gyrase

  Exonuclease

  Half-n-half Clue
 

3.

Because DNA polymerase III can only act from 5' to 3', continuous strand growth can be achieved only along one of the template strands (Leading strand) and strand growth along the other strand must occur discontinuously resulting in the production of a series of short sections of new DNA called :

  Replicon fragments

  Okazaki fragments

  Klenow fragments

  None of the above

  Half-n-half Clue
 

4.

In 1940, Nobel Laureate Barbara McClintock discovered sequences of DNA that can move around to different positions within the genome of a single cell and cause mutations. These sequences (first observed in maize) are called :

  Transposons

  inverted repeats

  direct repeats

  sticky ends

  Half-n-half Clue
 

5.

The enzyme that stitches Okazaki fragments together (along the lagging strand) is called :

  DNA Polymerase II

  DNA Ligase

  Topoisomerase

  Holoenzyme

  Half-n-half Clue
 

6.

Which of the following agents is not a mutagen ?

  Ultraviolet radiation

  A retrovirus

  A transposon or jumping gene

  None of the above

  Half-n-half Clue
 

7.

The enzyme responsible for initiating the unwinding of double-stranded DNA (eliminating supercoiling) by nicking a single strand of the DNA molecule is :

  Ligase

  Gyrase

  Helicase

  Topoisomerase

  Half-n-half Clue
 


 
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