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DNA Replication


This quiz is based on the process of DNA replication in both Prokaryotes and Eukaryotes.

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Multiple choice

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1.

In 1940, Nobel Laureate Barbara McClintock discovered sequences of DNA that can move around to different positions within the genome of a single cell and cause mutations. These sequences (first observed in maize) are called :

  Transposons

  inverted repeats

  direct repeats

  sticky ends

  Half-n-half Clue
 

2.

The enzyme that stitches Okazaki fragments together (along the lagging strand) is called :

  Topoisomerase

  DNA Ligase

  Holoenzyme

  DNA Polymerase II

  Half-n-half Clue
 

3.

An enzyme that recognizes and cuts DNA only at a particular sequence of nucleotides is often called :

  Restriction endonuclease

  RNA polymerase

  Photolyase

  DNA glycosylase

  Half-n-half Clue
 

4.

Because DNA polymerase III can only act from 5' to 3', continuous strand growth can be achieved only along one of the template strands (Leading strand) and strand growth along the other strand must occur discontinuously resulting in the production of a series of short sections of new DNA called :

  Replicon fragments

  Okazaki fragments

  Klenow fragments

  None of the above

  Half-n-half Clue
 

5.

The enzyme responsible for initiating the unwinding of double-stranded DNA (eliminating supercoiling) by nicking a single strand of the DNA molecule is :

  Gyrase

  Helicase

  Topoisomerase

  Ligase

  Half-n-half Clue
 

6.

What does transformation involve in Bacteria ?

  the infection of cells by a phage DNA molecule

  assimilation of external DNA into a cell

  the creation of a strand of RNA from DNA

  the creation of a strand of DNA from RNA

  Half-n-half Clue
 

7.

A mamalian cell typically has 1.2 meters (when completely outstretched) of double stranded DNA.The total time to duplicate the DNA is 5 hours. How many origins of replication are there if the rate of duplication is 16µmeters/min ?

  250

  15000

  1

  500

  Half-n-half Clue
 


 
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